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http://imsear.hellis.org/handle/123456789/91883
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| Title: | A multicentric study with arteether in patients of uncomplicated falciparum malaria. |
| Authors: | Asthana, O P
Srivastava, J S
Kamboj, V P
Valecha, N
Sharma, V P
Gupta, S
Pande, T K
Vishwanathan, K A
Mahapatra, K M
Nayak, N C
Mahapatra, P K
Mahanta, J
Srivastava, V K
Vasdev,
Singh, N
Shukla, M M
Balsara, A B
Mishra, S K
Satpathy, S K
Mohanty, S
Dash, B |
| Issue Date: | 28-Jul-2001 |
| Citation: | Asthana OP, Srivastava JS, Kamboj VP, Valecha N, Sharma VP, Gupta S, Pande TK, Vishwanathan KA, Mahapatra KM, Nayak NC, Mahapatra PK, Mahanta J, Srivastava VK, Vasdev , Singh N, Shukla MM, Balsara AB, Mishra SK, Satpathy SK, Mohanty S, Dash B. A multicentric study with arteether in patients of uncomplicated falciparum malaria. Journal of the Association of Physicians of India. 2001 Jul; 49(): 692-6 |
| Language: | eng |
| Type: | Clinical Trial
Clinical Trial, Phase III
Journal Article
Multicenter Study |
| Abstract: | Two hundred and sixty seven patients of uncomplicated P. falciparum malaria completed study in a multicentric phase III clinical trial of Arteether. Arteether was given intramuscularly in a dose of 150 mg daily for three consecutive days. Each patient was followed upto 28 days of alpha, beta arteether therapy. The cure rate was 97% with fever clearance time between 1-7 days (24-168 hours) and parasite clearance time between 1-3 days (24-72 hours). Parasite reappearance rate was found to be 3% and reported at only three of the centres. Following the treatment no adverse effect was observed on haematological, biochemical and vital clinical parameters. |
| Source URI: | http://www.japi.org |
| URI: | http://imsear.hellis.org/handle/123456789/91883 |
| MeSH: | Adolescent
Adult
Aged
Antimalarials --therapeutic use
Artemisinins
Female
Humans
Malaria, Falciparum --drug therapy
Male
Middle Aged
Sesquiterpenes --therapeutic use |
| Appears in Collections: | Journal of the Association of Physicians of India
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