Please use this identifier to cite or link to this item: http://imsear.hellis.org/handle/123456789/83440
Title: Detection of tubercule antigen in cerebrospinal fluids by ELISA for diagnosis of tuberculous meningitis.
Authors: Wagle, N
Vaidya, A
Joshi, S
Merchant, S M
Issue Date: 1-Sep-1990
Citation: Wagle N, Vaidya A, Joshi S, Merchant SM. Detection of tubercule antigen in cerebrospinal fluids by ELISA for diagnosis of tuberculous meningitis. Indian Journal of Pediatrics. 1990 Sep-Oct; 57(5): 679-83
Abstract: An Enzyme Linked Immunosorbent Assay (ELISA) was standardised to detect the presence of tubercule antigen in cerebrospinal fluids from patients with meningitis. CSF samples from clinically suspected cases of tuberculous meningitis, culture proven pyogenic meningitis and non-bacterial aseptic central nervous system (CNS) disorders were tested by ELISA to demonstrate its potential utility for routine diagnostic purpose. Tubercule antigen was detected in 73% cases of tuberculous meningitis and was absent in pyogenic and other non-bacterial CNS disorder cases. The test appears to be a promising approach for a definitive diagnosis of tuberculous meningitis.
URI: http://imsear.hellis.org/handle/123456789/83440
Appears in Collections:Indian Journal of Pediatrics

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