Please use this identifier to cite or link to this item:
Title: Treatment of invasive Aspergillosis in children with hematologic malignancies.
Authors: Abuhammour, Walid
Hasan, Rashed A
Issue Date: 28-Sep-2004
Citation: Abuhammour W, Hasan RA. Treatment of invasive Aspergillosis in children with hematologic malignancies. Indian Journal of Pediatrics. 2004 Sep; 71(9): 837-43
Abstract: The respiratory tract is the most common organ involved with Aspergillosis in children with hematologic malignancies. Also Aspergillus species tend to invade blood vessels resulting in systemic dissemination to multiple organs. Early diagnosis and treatment are pivotal to the patient's outcome. A high index of suspicion should be maintained in children who have profound neutropenia and present with prolonged fever that is unresponsive to systemic antibiotics. Several diagnostic modalities should be used simultaneously in order to confirm the diagnosis in an expedited manner. Combination and sequential antifungal therapy have been shown to be of added benefit. Surgical intervention is associated with a high mortality rate, but may be indicated in children with a localized disease. In this article the authors review the epidemiology, microbiology, pathology, and clinical manifestations of invasive aspergillosis in children with hematologic malignancies. Current diagnostic approach, medical, and surgical treatment options are discussed.
Description: 34 references.
Appears in Collections:Indian Journal of Pediatrics

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.