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|Title:||A simple broth-disk method to determine the minimum inhibitory concentration of ceftriaxone on Salmonella enterica serovar typhi and paratyphi.|
|Authors:||Bhat, K Gopalkrishna|
|Citation:||Bhat KG, Tripathy A, Rajagopal R, Ramachandran S. A simple broth-disk method to determine the minimum inhibitory concentration of ceftriaxone on Salmonella enterica serovar typhi and paratyphi. Indian Journal of Pathology & Microbiology. 2009 Apr-Jun; 52(2): 189-90|
|Abstract:||BACKGROUND AND PURPOSE: Resistance to fluoroquinolones and cephalosporins is a major problem with Salmonella enterica serovar Typhi and Paratyphi. An accurate determination of antibiotic susceptibility requires tests for minimum inhibitory concentration (MIC) of antibiotics. We describe a simple broth-disk method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi. MATERIALS AND METHODS: Sixteen strains of S. typhi and two strains each of S. paratyphi A and S. paratyphi B were used in the study. The MIC of ceftriaxone was determined using the simple broth-disk method and the conventional broth macrodilution method and the results were compared. RESULTS: All salmonella strains were susceptible to ceftriaxone. The results of the broth-disk and the conventional broth macrodilution method were similar. CONCLUSION: The broth-disk method is a simple, reliable and cost-effective method to determine the MIC of ceftriaxone on S. typhi and S. paratyphi A.|
|Appears in Collections:||Indian Journal of Pathology & Microbiology|
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