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Title: Aniridia-Wilms' tumour syndrome--a case report.
Authors: Vidyasagar, M S
Sagar, S V
Kumar, G R
Rao, P
Issue Date: 1-Oct-1992
Citation: Vidyasagar MS, Sagar SV, Kumar GR, Rao P. Aniridia-Wilms' tumour syndrome--a case report. Indian Journal of Ophthalmology. 1992 Oct-Dec; 40(4): 122-3
Abstract: Wilms' tumour is rarely associated with sporadic non-familial congenital aniridia. A child with sporadic aniridia has a 25% chance of subsequently developing Wilms' tumour. Unawareness of this association can lead to a delayed diagnosis of Wilms' tumour. One such case in a 2 year old is reported. Wilms' tumour, one of the common childhood malignancies, is associated with other congenital anomalies in about 15% of cases. These include hemihypertrophy, genitourinary abnormalities, mental retardation, aniridia etc. Sporadic non-familial aniridia was noted in only 1.1% of 547 children with Wilms' tumours evaluated by the National Wilms' Tumour study group. Unawareness on the part of a clinician about these associated anomalies can lead to an avoidable delay in diagnosing Wilms' tumour. One such case in a two year old girl is being reported.
Appears in Collections:Indian Journal of Ophthalmology

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