Please use this identifier to cite or link to this item: http://imsear.hellis.org/handle/123456789/71213
Title: Effect of combination antiretroviral therapy on cytomegalovirus retinitis.
Authors: Banker, Alay S
Patel, Atul
Issue Date: 2-Mar-2002
Citation: Banker AS, Patel A. Effect of combination antiretroviral therapy on cytomegalovirus retinitis. Indian Journal of Ophthalmology. 2002 Mar; 50(1): 29-33
Abstract: PURPOSE: To study the various changes in the course of cytomegalovirus (CMV) retinitis following combination antiretroviral treatment. METHODS: Combination antiretroviral treatment was given to 12 patients with active CMV retinitis following which all anti-CMV medications were discontinued once the CD4 cell counts were > 100/mm3 for 3 months. RESULTS: The median CD4 cell count increased from 36.5/mm3 (range, 3-74/mm3) at baseline to 175.5/mm3 (range, 97-410/mm3) at 3 months. No patient had reactivation of CMV retinitis or developed extraocular CMV infection during median follow-up of 16.7 months. In one patient with peripheral active CMV retinitis, the retinitis resolved completely and remained so throughout the follow-up period without specific anti-CMV treatment. Five (41.7%) patients had immune recovery vitritis. CONCLUSION: Patients receiving combination antiretroviral treatment following treatment for CMV retinitis have better control of CMV retinitis but immune recovery vitritis is a common sequelae. Reactivation of CMV retinitis is common in patients who discontinue combination antiretroviral treatment.
URI: http://imsear.hellis.org/handle/123456789/71213
Appears in Collections:Indian Journal of Ophthalmology

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