Please use this identifier to cite or link to this item: http://imsear.hellis.org/handle/123456789/57450
Title: Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis.
Authors: Sahare, K N
Anandhraman, V
Meshram, V G
Meshram, S U
Reddy, M V R
Tumane, P M
Goswami, K
Issue Date: 14-Feb-2008
Citation: Sahare KN, Anandhraman V, Meshram VG, Meshram SU, Reddy MV, Tumane PM, Goswami K. Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis. Indian Journal of Experimental Biology. 2008 Feb; 46(2): 128-31
Abstract: In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration showed complete loss of motility of microfilariae after 48 hr of incubation. Thin layer chromatography of the extracts revealed the presence of alkaloids, saponin and flavonoids in the roots of Vitex negundo L. and coumarin in the leaves of Aegle marmelos Corr.
URI: http://imsear.hellis.org/handle/123456789/57450
Appears in Collections:Indian Journal of Experimental Biology

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