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http://imsear.hellis.org/handle/123456789/112153
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| Title: | Comparative evaluation of blood schizontocidal activity of quinine and quinidine against drug resistant rodent malaria. |
| Authors: | Kazim, M
Puri, S K
Dutta, G P |
| Issue Date: | 1-Dec-1991 |
| Citation: | Kazim M, Puri SK, Dutta GP. Comparative evaluation of blood schizontocidal activity of quinine and quinidine against drug resistant rodent malaria. Journal of Communicable Diseases. 1991 Dec; 23(4): 254-6 |
| Language: | eng |
| Type: | Comparative Study
Journal Article |
| Abstract: | Blood schizontocidal activity of quinine and quinidine has been compared against sensitive as well as chloroquine/mefloquine/quinine resistant strains of Plasmodium berghei and a multiple resistant strain of P. yoelii nigeriensis in Swiss mice. Evaluation of results on ED50/ED90 basis has shown distinct superiority of quinidine over quinine against sensitive as well as drug resistant strain of rodent malaria. |
| URI: | http://imsear.hellis.org/handle/123456789/112153 |
| MeSH: | Animals
Drug Evaluation, Preclinical
Drug Resistance
Malaria --blood
Mice
Plasmodium berghei
Plasmodium yoelii
Quinidine --administration & dosage
Quinine --administration & dosage |
| Appears in Collections: | Journal of Communicable Diseases
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